ICD-10-CM diagnosis code
Z16.19 Resistance to other specified beta lactam antibiotics
- Billable
- Yes, a complete code (FY2026)
- Category
- Z16
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Other codes in Z16
19 complete codes in this category.
- Z16.10Resistance to unspecified beta lactam antibiotics
- Z16.11Resistance to penicillins
- Z16.12Extended spectrum beta lactamase (ESBL) resistance
- Z16.13Resistance to carbapenem
- Z16.19Resistance to other specified beta lactam antibiotics
- Z16.20Resistance to unspecified antibiotic
- Z16.21Resistance to vancomycin
- Z16.22Resistance to vancomycin related antibiotics
- Z16.23Resistance to quinolones and fluoroquinolones
- Z16.24Resistance to multiple antibiotics
- Z16.29Resistance to other single specified antibiotic
- Z16.30Resistance to unspecified antimicrobial drugs
Documentation tips
- Make sure the note supports every element of the title, “Resistance to other specified beta lactam antibiotics”: each detail in it should be traceable to the history, examination or assessment.
- Code to the highest specificity the documentation supports. If a detail is missing from the note, add it to the note rather than choosing a less specific code by default.
- Check the Tabular List and official guidelines for instructional notes (“code first”, “use additional code”, Excludes1/Excludes2) that apply to Z16.
ICD-10-CM is developed by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, and is based on the WHO ICD-10. Codes and titles are reproduced unchanged from the FY2026 code list (effective 1 October 2025). Their use here does not imply endorsement by CDC, HHS or the U.S. Government. Changes effective on or after 1 October 2026 may not be reflected yet; check the current release at cdc.gov or cms.gov before submitting claims.
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