ICD-10-CM diagnosis code
T80.61XA Other serum reaction due to administration of blood and blood products, initial encounter
- Billable
- Yes, a complete code (FY2026)
Encounter (7th character)
This code is for the initial encounter: the patient is receiving active treatment for the condition (for example surgery, an emergency department visit or evaluation by a new clinician).
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Other codes in T80
114 complete codes in this category.
- T80.52XAAnaphylactic reaction due to vaccination, initial encounter
- T80.52XDAnaphylactic reaction due to vaccination, subsequent encounter
- T80.52XSAnaphylactic reaction due to vaccination, sequela
- T80.59XAAnaphylactic reaction due to other serum, initial encounter
- T80.59XDAnaphylactic reaction due to other serum, subsequent encounter
- T80.59XSAnaphylactic reaction due to other serum, sequela
- T80.61XAOther serum reaction due to administration of blood and blood products, initial encounter
- T80.61XDOther serum reaction due to administration of blood and blood products, subsequent encounter
- T80.61XSOther serum reaction due to administration of blood and blood products, sequela
- T80.62XAOther serum reaction due to vaccination, initial encounter
- T80.62XDOther serum reaction due to vaccination, subsequent encounter
- T80.62XSOther serum reaction due to vaccination, sequela
Documentation tips
- Make sure the note supports every element of the title, “Other serum reaction due to administration of blood and blood products, initial encounter”: each detail in it should be traceable to the history, examination or assessment.
- Code to the highest specificity the documentation supports. If a detail is missing from the note, add it to the note rather than choosing a less specific code by default.
- Check the Tabular List and official guidelines for instructional notes (“code first”, “use additional code”, Excludes1/Excludes2) that apply to T80.
The international WHO ICD-10 also has T80, with its inclusion and exclusion notes; titles and detail can differ from ICD-10-CM.
ICD-10-CM is developed by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, and is based on the WHO ICD-10. Codes and titles are reproduced unchanged from the FY2026 code list (effective 1 October 2025). Their use here does not imply endorsement by CDC, HHS or the U.S. Government. Changes effective on or after 1 October 2026 may not be reflected yet; check the current release at cdc.gov or cms.gov before submitting claims.
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