ICD-10-CM category
D89 Other disorders involving the immune mechanism, not elsewhere classified
D89 is a category, not a billable code. Report one of the 24 complete codes below.
Codes in D89
- D89.0Polyclonal hypergammaglobulinemia
- D89.1Cryoglobulinemia
- D89.2Hypergammaglobulinemia, unspecified
- D89.3Immune reconstitution syndrome
- D89.40Mast cell activation, unspecified
- D89.41Monoclonal mast cell activation syndrome
- D89.42Idiopathic mast cell activation syndrome
- D89.43Secondary mast cell activation
- D89.44Hereditary alpha tryptasemia
- D89.49Other mast cell activation disorder
- D89.810Acute graft-versus-host disease
- D89.811Chronic graft-versus-host disease
- D89.812Acute on chronic graft-versus-host disease
- D89.813Graft-versus-host disease, unspecified
- D89.82Autoimmune lymphoproliferative syndrome [ALPS]
- D89.831Cytokine release syndrome, grade 1
- D89.832Cytokine release syndrome, grade 2
- D89.833Cytokine release syndrome, grade 3
- D89.834Cytokine release syndrome, grade 4
- D89.835Cytokine release syndrome, grade 5
- D89.839Cytokine release syndrome, grade unspecified
- D89.84IgG4-related disease
- D89.89Other specified disorders involving the immune mechanism, not elsewhere classified
- D89.9Disorder involving the immune mechanism, unspecified
Outside the US? D89 in the international WHO ICD-10 lists its inclusion and exclusion notes.
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ICD-10-CM is developed by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, and is based on the WHO ICD-10. Codes and titles are reproduced unchanged from the FY2026 code list (effective 1 October 2025). Their use here does not imply endorsement by CDC, HHS or the U.S. Government. Changes effective on or after 1 October 2026 may not be reflected yet; check the current release at cdc.gov or cms.gov before submitting claims.
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