ICD-10-CM category
D57 Sickle-cell disorders
D57 is a category, not a billable code. Report one of the 43 complete codes below.
D57.0…
6 codes
D57.1…
1 code
D57.2…
7 codes
- D57.20Sickle-cell/Hb-C disease without crisis
- D57.211Sickle-cell/Hb-C disease with acute chest syndrome
- D57.212Sickle-cell/Hb-C disease with splenic sequestration
- D57.213Sickle-cell/Hb-C disease with cerebral vascular involvement
- D57.214Sickle-cell/Hb-C disease with dactylitis
- D57.218Sickle-cell/Hb-C disease with crisis with other specified complication
- D57.219Sickle-cell/Hb-C disease with crisis, unspecified
D57.3…
1 code
D57.4…
21 codes
- D57.40Sickle-cell thalassemia without crisis
- D57.411Sickle-cell thalassemia, unspecified, with acute chest syndrome
- D57.412Sickle-cell thalassemia, unspecified, with splenic sequestration
- D57.413Sickle-cell thalassemia, unspecified, with cerebral vascular involvement
- D57.414Sickle-cell thalassemia, unspecified, with dactylitis
- D57.418Sickle-cell thalassemia, unspecified, with crisis with other specified complication
- D57.419Sickle-cell thalassemia, unspecified, with crisis
- D57.42Sickle-cell thalassemia beta zero without crisis
- D57.431Sickle-cell thalassemia beta zero with acute chest syndrome
- D57.432Sickle-cell thalassemia beta zero with splenic sequestration
- D57.433Sickle-cell thalassemia beta zero with cerebral vascular involvement
- D57.434Sickle-cell thalassemia beta zero with dactylitis
- D57.438Sickle-cell thalassemia beta zero with crisis with other specified complication
- D57.439Sickle-cell thalassemia beta zero with crisis, unspecified
- D57.44Sickle-cell thalassemia beta plus without crisis
- D57.451Sickle-cell thalassemia beta plus with acute chest syndrome
- D57.452Sickle-cell thalassemia beta plus with splenic sequestration
- D57.453Sickle-cell thalassemia beta plus with cerebral vascular involvement
- D57.454Sickle-cell thalassemia beta plus with dactylitis
- D57.458Sickle-cell thalassemia beta plus with crisis with other specified complication
- D57.459Sickle-cell thalassemia beta plus with crisis, unspecified
D57.8…
7 codes
- D57.80Other sickle-cell disorders without crisis
- D57.811Other sickle-cell disorders with acute chest syndrome
- D57.812Other sickle-cell disorders with splenic sequestration
- D57.813Other sickle-cell disorders with cerebral vascular involvement
- D57.814Other sickle-cell disorders with dactylitis
- D57.818Other sickle-cell disorders with crisis with other specified complication
- D57.819Other sickle-cell disorders with crisis, unspecified
Outside the US? D57 in the international WHO ICD-10 lists its inclusion and exclusion notes.
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ICD-10-CM is developed by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, and is based on the WHO ICD-10. Codes and titles are reproduced unchanged from the FY2026 code list (effective 1 October 2025). Their use here does not imply endorsement by CDC, HHS or the U.S. Government. Changes effective on or after 1 October 2026 may not be reflected yet; check the current release at cdc.gov or cms.gov before submitting claims.
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