ICD-10-CM diagnosis code
C78.5 Secondary malignant neoplasm of large intestine and rectum
- Billable
- Yes, a complete code (FY2026)
- Chapter
- 2. Neoplasms
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Other codes in C78
13 complete codes in this category.
- C78.01Secondary malignant neoplasm of right lung
- C78.02Secondary malignant neoplasm of left lung
- C78.1Secondary malignant neoplasm of mediastinum
- C78.2Secondary malignant neoplasm of pleura
- C78.30Secondary malignant neoplasm of unspecified respiratory organ
- C78.39Secondary malignant neoplasm of other respiratory organs
- C78.4Secondary malignant neoplasm of small intestine
- C78.5Secondary malignant neoplasm of large intestine and rectum
- C78.6Secondary malignant neoplasm of retroperitoneum and peritoneum
- C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
- C78.80Secondary malignant neoplasm of unspecified digestive organ
- C78.89Secondary malignant neoplasm of other digestive organs
Documentation tips
- Make sure the note supports every element of the title, “Secondary malignant neoplasm of large intestine and rectum”: each detail in it should be traceable to the history, examination or assessment.
- Code to the highest specificity the documentation supports. If a detail is missing from the note, add it to the note rather than choosing a less specific code by default.
- Check the Tabular List and official guidelines for instructional notes (“code first”, “use additional code”, Excludes1/Excludes2) that apply to C78.
The international WHO ICD-10 also has C78.5, with its inclusion and exclusion notes; titles and detail can differ from ICD-10-CM.
ICD-10-CM is developed by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, and is based on the WHO ICD-10. Codes and titles are reproduced unchanged from the FY2026 code list (effective 1 October 2025). Their use here does not imply endorsement by CDC, HHS or the U.S. Government. Changes effective on or after 1 October 2026 may not be reflected yet; check the current release at cdc.gov or cms.gov before submitting claims.
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