D81 is the ICD-10 code for Combined immunodeficiencies. It is a three-character category divided into 10 subcodes; use the subcode whenever the record supports that level of detail. It belongs to the block D80–D89 (Certain disorders involving the immune mechanism) in Chapter III, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.
- Code type
- Category (3 characters)
- Chapter
- III · D50–D89
- Classification
- WHO ICD-10, 2019 version
What D81 excludes
Conditions that look similar but belong under another code.
- autosomal recessive agammaglobulinaemia (Swiss type) D80.0
Subcodes of D81
- D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.3Adenosine deaminase [ADA] deficiency
- D81.4Nezelof syndrome
- D81.5Purine nucleoside phosphorylase [PNP] deficiency
- D81.6Major histocompatibility complex class I deficiency
- D81.7Major histocompatibility complex class II deficiency
- D81.8Other combined immunodeficiencies
- D81.9Combined immunodeficiency, unspecified
D81 in national editions
Countries report with their own edition of ICD-10. Most keep the WHO code and add more specific codes beneath it.
DD81Kombinerede immundefekter
D81Sekamuotoiset immuunivajavuudet
D81Kombinierte Immundefekte
D81Déficits immunitaires combinés
D81gecombineerde immunodeficiënties
Based on the World Health Organization’s International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10), 2019 version, and the national editions published by each country’s health authority. This page is a reference, not coding advice; follow your national coding rules when you report.
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